"Dad, turn down the TV, I have something to tell you," she said she told him. was her father, William Bertozzi, a retired physicist and night owl, who was still awake watching TV. Later, speaking to The Associated Press by Zoom, Bertozzi said one of the first people she called after being awakened by the call around 2 a.m. "I'm still not entirely positive that it's real, but it's getting realer by the minute." The goal is "doing chemistry inside human patients to make sure that drugs go to the right place and stay away from the wrong place," she said at a news conference following the announcement. Meldal, 68, based at the University of Copenhagen, and Sharpless, who is affiliated with Scripps Research in California, independently found the first such candidates that would easily snap together with each other but not with other molecules, leading to applications in the manufacture of medicines and polymers.īertozzi, 55, who is based at Stanford University "took click chemistry to a new level," the Nobel panel said, by finding a way to make the process work inside living organisms without disrupting them. "They have to react with each other easily and specifically." "The problem was to find good chemical buckles," he said. Sharpless, 81, who previously won a Nobel in 2001 and is now the fifth person to receive the prize twice, first proposed the idea of connecting molecules using chemical "buckles" around the turn of the millennium, Aqvist said. "It's all about snapping molecules together," said Johan Aqvist, a member of the Royal Swedish Academy of Sciences that announced the winners at the Karolinska Institute in Stockholm. Barry Sharpless, and Danish scientist Morten Meldal were cited for their work on click chemistry that works "sort of like molecular Lego." OrgId: AMAZON-4 Address: 1918 8th Ave City: SEATTLE StateProv: WA PostalCode: 98101-1244 Country: US RegDate: Updated: Ref: OrgAbuseHandle: AEA8-ARIN OrgAbuseName: Amazon EC2 Abuse OrgAbusePhone: +1-20 OrgAbuseEmail: OrgAbuseRef: OrgTechHandle: ANO24-ARIN OrgTechName: Amazon EC2 Network Operations OrgTechPhone: +1-20 OrgTechEmail: OrgTechRef: RTechHandle: AC6-ORG-ARIN RTechName: Amazon-com Incorporated RTechPhone: +1-20 RTechEmail: RTechRef: # ARIN WHOIS data and services are subject to the Terms of Use # available at: # If you see inaccuracies in the results, please report at # Copyright 1997-2018, American Registry for Internet Numbers, Ltd.Three scientists were jointly awarded this year's Nobel Prize in chemistry on Wednesday for developing a way of "snapping molecules together" that can be used to explore cells, map DNA and design drugs that can target diseases such as cancer more precisely.Īmericans Carolyn R. # ASNumber: 16509 ASName: AMAZON-02 ASHandle: AS16509 RegDate: Updated: Ref: OrgName:, Inc. # ARIN WHOIS data and services are subject to the Terms of Use # available at: # If you see inaccuracies in the results, please report at # Copyright 1997-2018, American Registry for Internet Numbers, Ltd. Relying Google MobileFriendly test is well optimized for mobile and tablet devices.
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